Recombinant人LIGHT protein (ab109159)

概述

描述

  • 性质Recombinant
  • 来源CHO cells
  • 氨基酸序列
    • AccessionO43557
    • 种属Human
    • 分子量25 kDa including tags
    • 氨基酸89 to 240
    • 标签DDDDK tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab109159 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 纯度> 95 % SDS-PAGE.

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

  • 复溶Reconstitute with 100 µl sterile water. PBS containing at least 0.1% BSA should be used for further dilutions.

常规信息

  • 别名
    • CD 258
    • CD258
    • CD258 antigen
    • Delta transmembrane LIGHT
    • Herpes virus entry mediator ligand
    • Herpesvirus entry mediator A
    • Herpesvirus entry mediator ligand
    • herpesvirus entry mediator-ligand
    • HVEM L
    • HVEM-L
    • HVEML
    • Ligand for herpesvirus entry mediator
    • LIGHT
    • LTg
    • soluble form
    • TNF14
    • TNF14_HUMAN
    • TNFSF 14
    • Tnfsf14
    • TNFSF14 protein
    • TR 2
    • TR2
    • Tumor necrosis factor (ligand) superfamily, member 14
    • Tumor necrosis factor ligand superfamily member 14
    • Tumor necrosis factor ligand superfamily, member 14
    • Tumor necrosis factor receptor like 2
    • tumor necrosis factor receptor-like 2
    • Tumor necrosis factor superfamily member 14
    • Tumor necrosis factor superfamily member LIGHT
    see all
  • 功能Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
  • 组织特异性Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
  • 序列相似性Belongs to the tumor necrosis factor family.
  • 翻译后修饰N-glycosylated.
    The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
  • 细胞定位Cytoplasm; Secreted and Cell membrane.
  • Information by UniProt

Recombinant Human LIGHT protein (ab109159)参考文献

ab109159 has not yet been referenced specifically in any publications.

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