Recombinant人LIF protein (ab99450)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP15018
    • 种属Human
    • 分子量20 kDa
    • 氨基酸23 to 202

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技术指标

Our Abpromise guarantee covers the use of ab99450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性The ED50 determined by the M1 cell differentiation assay is < 0.01 ng/ml, corresponding to a specific activity of 100 MIU/mg.
  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Purity is >95% by SDS-PAGE and HPLC analyses.
  • 形式Lyophilised
  • 补充说明Endotoxin level is <0.1 ng per µg.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 1X PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week, or as working aliquots at –20°C for future use. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

常规信息

  • 别名
    • CDF
    • Cholinergic Differentiation Factor
    • D factor
    • DIA
    • Differentiation inducing factor
    • differentiation inhibitory activity
    • Differentiation stimulating factor
    • Differentiation-stimulating factor
    • Emfilermin
    • Hepatocyte stimulating factor III
    • HILDA
    • Human interleukin in DA cells
    • Leukemia inhibitory factor
    • LIF
    • LIF_HUMAN
    • Melanoma derived LPL inhibitor
    • Melanoma-derived LPL inhibitor
    • MLPLI
    see all
  • 功能LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
  • 序列相似性Belongs to the LIF/OSM family.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant human LIF protein (ab99450)参考文献

ab99450 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"