Recombinant人Leptin Triple Mutant protein (ab73583)

概述

  • 产品名称Recombinant人Leptin Triple Mutant protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Pro-Ile-Gln.

技术指标

Our Abpromise guarantee covers the use of ab73583 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Inhibition Assay

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab73583 is purified by proprietary chromatographic techniques. Purity is greater than 98.0% as determined by Gel filtration analysis and analysis by SDS-PAGE.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 0.0045mM Sodium phosphate

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Reconstitute in sterile 0.4% NaHCO3 adjusted to pH 8-9, not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Upon reconstitution at > 0.1 mg/ml and up to 2 mM and filter sterilization ab73583 can be stored at 4°C or even room temperature for several weeks making it suitable for long term infusion studies using osmotic pumps. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is suggested. Please prevent freeze-thaw cycles.

常规信息

  • 别名
    • LEP
    • LEP_HUMAN
    • Leptin
    • Obese protein
    • Obesity factor
    see all
  • 功能May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
  • 疾病相关Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
  • 序列相似性Belongs to the leptin family.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant human Leptin Triple Mutant protein (ab73583)参考文献

ab73583 has not yet been referenced specifically in any publications.

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