Recombinant人Leptin protein (ab119739)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP48357
    • 种属Human
    • 序列The sequence of the first four N-terminal amino acids was determined and was found to be Ala-Thr-Pro-Val.
    • 分子量25 kDa
    • 氨基酸428 to 635

技术指标

Our Abpromise guarantee covers the use of ab119739 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Biological Activity is evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio
  • 应用

    Functional Studies

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Store under Desiccating conditions.

    Constituent: 0.00004% Sodium bicarbonate

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Centrifuge the vial prior to opening. The lyophilized Leptin Binding Domain is very soluble in water and most aqueous buffers below and above the isoelectric point (~ 5.9). The reconstituted protein should be stored at 4°C. Avoid freeze/thaw cycles.

常规信息

  • 别名
    • FLJ94114
    • LEP
    • LEP_HUMAN
    • LEPD
    • Leptin
    • Leptin (murine obesity homolog)
    • Leptin (obesity homolog, mouse)
    • Leptin Murine Obesity Homolog
    • Leptin Precursor Obesity Factor
    • OB
    • Obese protein
    • Obese, mouse, homolog of
    • Obesity
    • Obesity factor
    • Obesity homolog mouse
    • Obesity Murine Homolog Leptin
    • OBS
    • OTTHUMP00000212285
    see all
  • 功能May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
  • 疾病相关Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
  • 序列相似性Belongs to the leptin family.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant human Leptin protein (ab119739)参考文献

ab119739 has not yet been referenced specifically in any publications.

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