Recombinant人LECT1 protein (ab112725)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO75829
    • 种属Human
    • 分子量38 kDa

技术指标

Our Abpromise guarantee covers the use of ab112725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    pH: 6.80
    Constituents: 1.58% Tris HCl, 3.09% DTT, 4% SDS, 0.2% Bromophenol blue, 20% Sucrose

  • 复溶Add 100ul of distilled water.

常规信息

  • 别名
    • BRICD3
    • BRICHOS domain containing 3
    • CH-SP
    • CHM I
    • ChM-I
    • CHM1
    • chondromodulin
    • Chondromodulin I
    • Chondromodulin-1
    • Chondromodulin-I
    • Chondrosurfactant protein
    • LECT 1
    • Lect1
    • LECT1_HUMAN
    • Leukocyte cell derived chemotaxin 1
    • Multiple myeloma tumor suppressor 1
    • MYETS1
    see all
  • 功能Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
  • 组织特异性Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma.
  • 序列相似性Belongs to the chondromodulin-1 family.
    Contains 1 BRICHOS domain.
  • 发展阶段Expressed at 9 weeks in developing cartilagenous bone rudiments.
  • 翻译后修饰After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.
  • 细胞定位Endomembrane system and Secreted. Accumulated in the inter-territorial matrix of cartilage.
  • Information by UniProt

Recombinant Human LECT1 protein (ab112725)参考文献

ab112725 has not yet been referenced specifically in any publications.

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