The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
内毒素水平< 0.100 Eu/µg
补充说明The biological activity of this product is determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.
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Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
C-C motif chemokine 16
Chemokine (C-C motif) ligand 16
IL10 inducible chemokine
Liver CC chemokine 1 precursor
Liver expressed chemokine
Lymphocyte and monocyte chemoattractant
New CC chemokine 4
Small inducible cytokine A16 precursor
Small inducible cytokine subfamily A (Cys Cys) member 16
Small-inducible cytokine A16
功能Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
组织特异性Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
序列相似性Belongs to the intercrine beta (chemokine CC) family.