概述

  • 产品名称
    重组人Kv1.4蛋白
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      NFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEY LEMEEGVKESLCAKEEKCQGKGDDSETDKNNCSNAKAVETD
    • 分子量
      36 kDa including tags
    • 氨基酸
      562 to 652

技术指标

Our Abpromise guarantee covers the use of ab152487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Voltage gated K+ channel HuKII
    • Fetal skeletal muscle potassium channel
    • HBK4
    • HK1
    • HPCN2
    • HUKII
    • Kcna4
    • KCNA4_HUMAN
    • KCNA4L
    • KCNA8
    • kv1.4
    • PCN2
    • Potassium channel 2
    • Potassium voltage gated channel shaker related subfamily member 4
    • Potassium voltage gated channel subfamily A member 4
    • Potassium voltage-gated channel subfamily A member 4
    • Rapidly inactivating potassium channel
    • Shaker related potassium channel Kv1.4
    • Type A potassium channel
    • Voltage gated potassium channel HBK4
    • Voltage gated potassium channel HK1
    • Voltage gated potassium channel subunit Kv1.4
    • Voltage-gated K(+) channel HuKII
    • Voltage-gated potassium channel HBK4
    • Voltage-gated potassium channel HK1
    • Voltage-gated potassium channel subunit Kv1.4
    see all
  • 功能
    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • 序列相似性
    Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
  • 结构域
    The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 细胞定位
    Membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152487 stained with Coomassie Blue.

文献

ab152487 has not yet been referenced specifically in any publications.

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