Recombinant人Ku70 + Ku80 protein (ab73790)

概述

  • 产品名称Recombinant人Ku70 + Ku80 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human
    • 额外的序列信息KuP70/P80 Human Recombinant produced in SF9 insect cells is a glycosylated, polypeptide chain having a molecular mass of 70,638 Dalton for the p70 subunit and 83,528 Dalton for the p80 subunit.

技术指标

Our Abpromise guarantee covers the use of ab73790 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

  • 纯度> 90 % SDS-PAGE.
    This antibody is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 160mM Sodium chloride, 16mM HEPES, pH 8

常规信息

  • 别名
    • CTC75
    • CTC85
    • CTCBF
    • DNA repair protein XRCC5
    • DNA repair protein XRCC6
    • G22P1
    • G22P2
    • KARP1
    • Ku 70
    • Ku 80
    • Ku 86
    • Ku86
    • ML8
    • NFIV
    • TLAA
    • XRCC5
    • XRCC6
    see all
  • 相关性The Ku autoantigen is a heterodimer of 70kDa (p70) and 80kDa (p80) proteins. The p70 / p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. The Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
  • 细胞定位Nuclear

Recombinant Human Ku70 + Ku80 protein (ab73790)参考文献

ab73790 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. A suitable detection antibody could be against the His tag. For example HRP conjugated: ab1187 ab1269 ab3553 Detection of Ku70/Ku80 heterodimer by Ku antibodies may bear false-negative results since the main reacti...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"