概述
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产品名称Recombinant人KMT5C/SUV4-20h2 protein
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蛋白长度Protein fragment
描述
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性质Recombinant
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来源Escherichia coli
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氨基酸序列
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种属Human
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氨基酸2 to 280
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技术指标
Our Abpromise guarantee covers the use of ab80290 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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纯度> 90 % SDS-PAGE.
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形式Liquid
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Preservative: None
Constituents: 30% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
常规信息
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别名
- FLJ98627
- Histone lysine N methyltransferase SUV420H2
- Histone-lysine N-methyltransferase SUV420H2
see all -
功能Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
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序列相似性Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
Contains 1 SET domain. -
细胞定位Nucleus. Chromosome. Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin.
- Information by UniProt
Recombinant Human KMT5C/SUV4-20h2 protein 图像
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SDS-PAGE - KMT5C/SUV4-20h2 protein (Tagged) (ab80290)10% SDS-PAGE showing ab80290 at approximately 58kDa (5µg).
Recombinant Human KMT5C/SUV4-20h2 protein (ab80290)参考文献
ab80290 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"