Recombinant人Kir6.2 protein (ab114436)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ14654
    • 种属Human
    • 序列RTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLD EDHSLLEALTLASARGPLRKRSVPMAKAKPKFSISPDSLS
    • 分子量36 kDa including tags
    • 氨基酸301 to 390

技术指标

Our Abpromise guarantee covers the use of ab114436 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • ATP sensitive inward rectifier potassium channel 11
    • Beta cell inward rectifier subunit
    • BIR
    • HHF 2
    • HHF2
    • IKATP
    • Inward rectifier K(+) channel Kir6.2
    • Inwardly rectifying potassium channel KIR6.2
    • IRK 11
    • IRK11
    • KCNJ11
    • Kir 6.2
    • Kir6.2
    • MGC133230
    • PHHI
    • Potassium channel inwardly rectifing subfamily J member 11
    • Potassium channel, inwardly rectifying subfamily J member 11
    • Potassium inwardly rectifying channel J11
    • TNDM 3
    • TNDM3
    see all
  • 相关性ATP-sensitive potassium (K(ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K(ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus.
  • 细胞定位Cell Membrane; Multi-pass membrane protein

Recombinant Human Kir6.2 protein 图像

  • ab114436 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Recombinant Human Kir6.2 protein (ab114436)参考文献

ab114436 has not yet been referenced specifically in any publications.

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