概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MERPIKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWR IAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDI ILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLM TICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITF LSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHV HNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFL QAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQ IGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTT HTPISDSPIGVSSTSFPTPYTSSSSC
    • 分子量
      73 kDa including tags
    • 氨基酸
      1 to 426

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技术指标

Our Abpromise guarantee covers the use of ab152490 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • hSK3
    • KCa2.3
    • Kcnn3
    • KCNN3_HUMAN
    • Potassium calcium activated channel subfamily N member 3
    • Potassium channel calcium activated intermediate/small conductance subfamily N alpha member 3
    • Potassium channel, calcium activated, intermediate/small conductance, subfamily N, member 3
    • Potassium intermediate/small conductance calcium activated channel subfamily N member 3
    • SK3
    • SKCa 3
    • SKCa3
    • Small conductance calcium-activated potassium channel protein 3
    see all
  • 功能
    Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
  • 序列相似性
    Belongs to the potassium channel KCNN family. KCa2.3/KCNN3 subfamily.
  • 细胞定位
    Membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152490 stained with Coomassie Blue.

文献

ab152490 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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