Recombinant人KCNA3 protein (ab114518)

概述

  • 产品名称
    Recombinant人KCNA3 protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      VPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLS KSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
    • 分子量
      37 kDa including tags
    • 氨基酸
      476 to 575

技术指标

Our Abpromise guarantee covers the use of ab114518 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • HGK 5
    • HGK5
    • HLK 3
    • HLK3
    • HPCN 3
    • HPCN3
    • HuKIII
    • KCNA 3
    • Kcna3
    • KCNA3_HUMAN
    • KV1.3
    • MK 3
    • MK3
    • OTTHUMP00000032397
    • PCN 3
    • PCN3
    • Potassium channel 3
    • Potassium voltage gated channel shaker related subfamily member 3
    • Potassium voltage gated channel subfamily A member 3
    • Potassium voltage-gated channel subfamily A member 3
    • Type n potassium channel
    • Voltage gated potassium channel protein Kv1.3
    • Voltage gated potassium channel subunit Kv1.3
    • Voltage-gated K(+) channel HuKIII
    • Voltage-gated potassium channel subunit Kv1.3
    see all
  • 功能
    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • 序列相似性
    Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily.
  • 结构域
    The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 细胞定位
    Membrane.
  • Information by UniProt

图片

  • ab114518 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

文献

ab114518 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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