Recombinant人KAT2B / PCAF protein (ab82074)

概述

描述

  • 性质
    Recombinant
  • 来源
    Baculovirus
  • 氨基酸序列
    • 种属
      Human

技术指标

Our Abpromise guarantee covers the use of ab82074 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    1 unit equals 1 nanogram of purified protein.
  • 应用

    EMSA

  • 形式
    Liquid
  • 补充说明
    1 unit equals 1 nanogram of purified protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8

常规信息

  • 别名
    • CAF
    • CREBBP associated factor
    • GCN5
    • GCN5L
    • GCN5L1
    • Histone acetylase PCAF
    • Histone acetyltransferase KAT2B
    • Histone acetyltransferase PCAF
    • K(lysine) acetyltransferase 2B
    • KAT2B
    • KAT2B_HUMAN
    • Lysine acetyltransferase 2B
    • P
    • P/CAF
    • p300/CBP associated factor
    • P300/CBP-associated factor
    • Pcaf
    see all
  • 功能
    Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
  • 组织特异性
    Ubiquitously expressed but most abundant in heart and skeletal muscle.
  • 序列相似性
    Belongs to the GCN5 family.
    Contains 1 bromo domain.
    Contains 1 N-acetyltransferase domain.
  • 结构域
    The bromodomain mediates binding to HIV-1 Tat.
  • 细胞定位
    Nucleus.
  • Information by UniProt

Recombinant Human KAT2B / PCAF protein (ab82074)参考文献

ab82074 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab82074.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册