Recombinant人ITLN1 protein (ab109151)

概述

描述

  • 性质Recombinant
  • 来源CHO cells
  • 氨基酸序列
    • AccessionQ8WWA0
    • 种属Human
    • 分子量38 kDa including tags
    • 氨基酸17 to 313
    • 标签DDDDK tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab109151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Enhances glucose transport mediated by insulin.
  • 应用

    Functional Studies

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 纯度> 95 % SDS-PAGE.

  • 形式Lyophilised
  • 补充说明After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. Enhances glucose transport mediated by insulin.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.

    Preservative: None
    Constituents: PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Reconstitute with 100µl sterile water to give a final concentration of 0.1mg/ml.

常规信息

  • 别名
    • Endothelial lectin HL 1
    • Endothelial lectin HL-1
    • FLJ20022
    • Galactofuranose binding lectin
    • Galactofuranose-binding lectin
    • hIntL
    • HL 1
    • HL1
    • Intelectin
    • Intelectin 1
    • Intelectin-1
    • Intestinal lactoferrin receptor
    • INTL
    • ITLN
    • ITLN-1
    • ITLN1
    • ITLN1_HUMAN
    • LFR
    • Omentin
    • OTTHUMP00000027882
    see all
  • 功能Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.
  • 组织特异性Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus.
  • 序列相似性Contains 1 fibrinogen C-terminal domain.
  • 发展阶段Found in fetal small intestine and thymus.
  • 翻译后修饰N-glycosylated.
  • 细胞定位Cell membrane. Secreted. Enriched in lipid rafts.
  • Information by UniProt

Recombinant human ITLN1 protein (ab109151)参考文献

ab109151 has not yet been referenced specifically in any publications.

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Our products are designed for research purposes and have not been tested for treatment in animal studies. There doesn't appear to be anything in the buffer for this product that would be incompatible with using it...

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