概述

描述

  • 性质
    Recombinant
  • 来源
    Insect cells
  • 氨基酸序列
    • 种属
      Human
    • 标签
      GST tag N-Terminus

相关产品

技术指标

Our Abpromise guarantee covers the use of ab60859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

    SDS-PAGE

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride, 0.3% Glutathione

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • il1rak2
    • Interleukin 1 receptor associated kinase 2
    • Interleukin 1 receptor associated kinase like 2
    • Interleukin-1 receptor-associated kinase-like 2
    • IRAK 2
    • IRAK-2
    • Irak2
    • IRAK2_HUMAN
    • MGC150550
    see all
  • 功能
    Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
  • 组织特异性
    Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
  • 序列相似性
    Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
    Contains 1 death domain.
    Contains 1 protein kinase domain.
  • 结构域
    The protein kinase domain is predicted to be catalytically inactive.
  • Information by UniProt

图片

  • Sample Kinase Activity Plot.
  • ab60859 on SDS-PAGE, MW ~103 kDa.

文献

ab60859 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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