功能Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
组织特异性Keratinocytes of epidermis and other stratified squamous epithelia.
序列相似性Belongs to the involucrin family.
翻译后修饰Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide.
细胞定位Cytoplasm. Constituent of the scaffolding of the cornified envelope.