The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 50% Glycerol, 20mM Tris HCl, pH 8
Fatty acid binding protein
Fatty acid binding protein 2 intestinal
Fatty acid binding protein intestinal
Fatty acid-binding protein
Fatty acid-binding protein 2
Intestinal fatty acid binding protein 2
Intestinal-type fatty acid-binding protein
功能FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
组织特异性Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.
序列相似性Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
结构域Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.