Recombinant人intestinal FABP protein (ab115502)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MKHHHHHHASAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTI TQEGNKFTVKESSAFRNIEVVFELGVTFNYNLADGTELRGTWSLEGNKLI GKFKRTDNGNELNTVREIIGDELVQTYVYEGVEAKRIFKKD
    • 分子量
      16 kDa including tags
    • 氨基酸
      2 to 131
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab115502 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 内毒素水平
    < 1.000 Eu/µg
  • 纯度
    > 95 % SDS-PAGE.
    ab115502 is purified using Ni-NTA chromatography.
  • 形式
    Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -80°C.

    pH: 7.40
    Constituents: 0.29% Sodium chloride, 0.69% Phosphate Buffer

  • 复溶
    Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at –80°C for long term storage. Reconstituted protein can be stored at 4°C for a week.

常规信息

  • 别名
    • FABP 2
    • FABP2
    • FABPI
    • FABPI_HUMAN
    • Fatty acid binding protein
    • Fatty acid binding protein 2 intestinal
    • Fatty acid binding protein intestinal
    • Fatty acid-binding protein
    • Fatty acid-binding protein 2
    • I FABP
    • I-FABP
    • IFABP
    • intestinal
    • Intestinal fatty acid binding protein 2
    • Intestinal-type fatty acid-binding protein
    • MGC133132
    • OTTHUMP00000163925
    see all
  • 功能
    FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
  • 组织特异性
    Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.
  • 序列相似性
    Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • 结构域
    Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

图片

  • 14% SDS-PAGE showing ab115502
    Lane 1: M.W. marker – 14, 21, 31, 45, 66, 97 kDa
    Lane 2: reduced and boiled sample, 5µg/lane.
    Lane 3: non-reduced and non-boiled sample, 5µg/lane.

文献

ab115502 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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