Recombinant人Insulin Receptor R protein (ab69988)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • AccessionP14616
    • 种属Human
    • 分子量65 kDa
    • 标签GST tag N-Terminus
    • 额外的序列信息Recombinant human fragment of Insulin Receptor R (945-end).

技术指标

Our Abpromise guarantee covers the use of ab69988 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific activity: 111 nmol/min/mg as per kinase assay.
  • 应用

    Functional Studies

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.

  • 形式Liquid
  • 补充说明

    ab204853 (IRS1 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • INSRR
    • INSRR_HUMAN
    • Insulin receptor related receptor precursor
    • Insulin receptor-related protein alpha chain
    • Insulin receptor-related protein beta chain
    • insulin receptor-related receptor
    • IR R
    • IR related receptor
    • IR-related receptor
    • IRR
    • Sir r
    • Sirr
    see all
  • 功能This receptor probably binds an insulin related protein and has a tyrosine-protein kinase activity. It phosphorylates the insulin receptor substrates IRS-1 and IRS-2.
  • 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    Contains 3 fibronectin type-III domains.
    Contains 1 protein kinase domain.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant human Insulin Receptor R protein 图像

  • Insulin Receptor R enzymatic activity.
  • SDS page analysis of ab69988

Recombinant human Insulin Receptor R protein (ab69988)参考文献

ab69988 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your recent telephone enquiry.

I am sorry to confirm, as we discussed on the telephone, that ab69988 Insulin Receptor R protein has not been tested and guaranteed in binding assays, and has not been tested with ab123768 insulin...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"