Recombinant人Insulin protein (ab73797)



  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 分子量6 kDa
    • 额外的序列信息ab73797 is a two chain (aa 90-110 insulin A, aa 25-54 insulin B), non-glycosylated polypeptide chain containing 51 amino acids and having a molecular mass of 5807 Dalton.


Our Abpromise guarantee covers the use of ab73797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性

    28 units/mg

  • 应用


    Functional Studies

  • 纯度> 95 % SDS-PAGE.
    ab73797 is purified by proprietary chromatographic techniques. Purity is greater than 98.0% as determined by RP-HPLC and SDS-PAGE.
  • 形式Lyophilised
  • 补充说明

    Lyophilized Insulin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Insulin should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.


    Two chain, non-glycosylated polypeptide chain containing 51 amino acids and having a molecular mass of 5807 Dalton consisting of human insulin A (21 aa) and B (30 aa) chains

  • Concentration information loading...


  • 稳定性和存储

    Shipped at 4°C. Please see notes section.

    Preservative: None

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Reconstitute the lyophilized Insulin in sterile 0.005N HCl to not more than 1 mg/ml.


  • 别名
    • IDDM1
    • IDDM2
    • ILPR
    • ins
    • Insulin A chain
    • Insulin B chain
    • IRDN
    • MODY10
    • Preproinsulin
    • Proinsulin
    • Proinsulin precursor
    see all
  • 功能Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
  • 疾病相关Defects in INS are the cause of familial hyperproinsulinemia (FHPRI) [MIM:176730].
    Defects in INS are a cause of diabetes mellitus insulin-dependent type 2 (IDDM2) [MIM:125852]. IDDM2 is a multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
    Defects in INS are a cause of diabetes mellitus permanent neonatal (PNDM) [MIM:606176]. PNDM is a rare form of diabetes distinct from childhood-onset autoimmune diabetes mellitus type 1. It is characterized by insulin-requiring hyperglycemia that is diagnosed within the first months of life. Permanent neonatal diabetes requires lifelong therapy.
    Defects in INS are a cause of maturity-onset diabetes of the young type 10 (MODY10) [MIM:613370]. MODY10 is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease.
  • 序列相似性Belongs to the insulin family.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant human Insulin protein (ab73797)参考文献

ab73797 has not yet been referenced specifically in any publications.

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Thank you for contacting us. You can ask any questions to us we are happy to help. We can only guarantee these proteins acting as inducers in functional assays in human cells. These proteins are tested only with human cells. The RAT insulin 1, ...

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