Cytotoxic T lymphocyte associated serine esterase 8
Cytotoxic T-lymphocyte-associated antigen 8
Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8)
功能Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
组织特异性Restricted to activated memory T-cells.
序列相似性Belongs to the IL-17 family.
翻译后修饰Found both in glycosylated and nonglycosylated forms.