Recombinant人IL17 protein (ab73202)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 序列
      The sequence of the first five N-terminal amino acids was determined and was found to be, Gly-Ile-Thr-Ile-Pro.
    • 分子量
      31 kDa

技术指标

Our Abpromise guarantee covers the use of ab73202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    Biological Activity: The ED50 as determined by the dose-dependent induction of IL6 in Hs68 cell line was found to be approximately 2ng/ml.
  • 应用

    Western blot

    SDS-PAGE

    Functional Studies

  • 纯度
    > 95 % SDS-PAGE.
    ab73202 is purified by proprietary chromatographic techniques. Purity is greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
  • 形式
    Lyophilised
  • 补充说明
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 0.1M Sodium chloride, 20mM Citrate, pH 4.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶
    Reconstitute in sterile 18MOhm-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

常规信息

  • 别名
    • CTLA 8
    • CTLA-8
    • CTLA8
    • Cytotoxic T lymphocyte associated antigen 8
    • Cytotoxic T lymphocyte associated protein 8
    • Cytotoxic T lymphocyte associated serine esterase 8
    • Cytotoxic T-lymphocyte-associated antigen 8
    • IL 17A
    • IL-17
    • IL-17A
    • IL17
    • IL17_HUMAN
    • Il17a
    • Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8)
    • Interleukin 17A
    • Interleukin-17A
    • Interleukin17
    • Interleukin17A
    • OTTHUMP00000016597
    • OTTMUSP00000046003
    see all
  • 功能
    Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
  • 组织特异性
    Restricted to activated memory T-cells.
  • 序列相似性
    Belongs to the IL-17 family.
  • 翻译后修饰
    Found both in glycosylated and nonglycosylated forms.
  • 细胞定位
    Secreted.
  • Information by UniProt

Recombinant human IL17 protein 图像

  • Anti-IL17 antibody (ab77171) at 1 µg/ml + Recombinant human IL17 protein (ab73202) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 1 minute

Recombinant human IL17 protein (ab73202)参考文献

ab73202 has not yet been referenced specifically in any publications.

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