概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS

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技术指标

Our Abpromise guarantee covers the use of ab49835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    Inhibition Assay

    Functional Studies

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 纯度> 95 % SDS-PAGE.
    Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10mM Sodium citrate, pH 4
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).

  • 复溶Reconstitute in water to a concentration of 0.1-1.0 mg/ml.

常规信息

  • 别名
    • IBP 5
    • IBP-5
    • IBP5
    • IBP5_HUMAN
    • IGF binding protein 5
    • IGF BP5
    • IGF-binding protein 5
    • IGFBP 5
    • IGFBP-5
    • IGFBP5
    • Insulin like growth factor binding protein 5
    • Insulin-like growth factor-binding protein 5
    see all
  • 功能IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • 组织特异性Osteosarcoma, and at lower levels in liver, kidney and brain.
  • 序列相似性Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant Human IGFBP5 protein 图像

  • Anti-IGFBP5 antibody (Biotin) (ab84229) at 0.1 µg/ml + Recombinant Human IGFBP5 protein (ab49835) at 0.01 µg

    Secondary
    Goat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 30 seconds

Recombinant Human IGFBP5 protein (ab49835)参考文献

This product has been referenced in:
  • Abrass CK & Hansen KM Insulin-like growth factor-binding protein-5-induced laminin gamma1 transcription requires filamin A. J Biol Chem 285:12925-34 (2010). Read more (PubMed: 20167606) »

See 1 Publication for this product

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