Recombinant人HSD17B8 protein (ab125640)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHH SSGLVPRGSH MASQLQNRLR SALALVTGAG SGIGRAVSVR LAGEGATVAA CDLDRAAAQE TVRLLGGPGS KEGPPRGNHA AFQADVSEAR AARCLLEQVQ ACFSRPPSVV VSCAGITQDE FLLHMSEDDW DKVIAVNLKG TFLVTQAAAQ ALVSNGCRGS IINISSIVGK VGNVGQTNYA ASKAGVIGLT QTAARELGRH GIRCNSVLPG FIATPMTQKV PQKVVDKITE MIPMGHLGDP EDVADVVAFL ASEDSGYITG TSVEVTGGLF M
    • 分子量
      29 kDa including tags
    • 氨基酸
      1 to 261
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab125640 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.
    Purified by proprietary chromatographic techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride

常规信息

  • 别名
    • 17 beta HSD 8
    • 17 beta hydroxysteroid dehydrogenase 8
    • 17-beta-HSD 8
    • 17-beta-hydroxysteroid dehydrogenase 8
    • 17-beta-hydroxysteroid dehydrogenase VIII
    • 3-oxoacyl-[acyl-carrier-protein] reductase
    • 3-oxoacyl-acyl-carrier protein reductase, E. coli, homolog of
    • Beta ketoacyl [acyl carrier protein] reductase like
    • D6S2245E
    • DHB8_HUMAN
    • dJ1033B10.9
    • Estradiol 17 beta dehydrogenase 8
    • Estradiol 17-beta-dehydrogenase 8
    • Estrogen 17 oxidoreductase
    • FABG
    • FabG, E. coli, homolog of
    • FabG-like
    • FABGL
    • H2 KE6
    • H2-KE6
    • HKE6
    • HSD17B8
    • Hydroxysteroid (17 beta) dehydrogenase 8
    • Ke-6
    • KE6
    • KE6, mouse homolog of
    • Protein Ke6
    • Really interesting new gene 2 protein
    • RING2
    • SDR30C1
    • Short chain dehydrogenase/reductase family 30C member 1
    • Testosterone 17 beta dehydrogenase 8
    • Testosterone 17-beta-dehydrogenase 8
    see all
  • 功能
    NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
  • 组织特异性
    Highly expressed in placenta, liver and pancreas, lower in the skeletal muscle and kidney. Widely expressed.
  • 通路
    Steroid biosynthesis; estrogen biosynthesis.
    Lipid metabolism; fatty acid biosynthesis.
  • 序列相似性
    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 细胞定位
    Mitochondrion matrix.
  • Information by UniProt

文献

ab125640 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab125640.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册