Recombinant人Hsd17b11 protein (ab101826)

概述

  • 产品名称Recombinant人Hsd17b11 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ8NBQ5
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMESFVKLFIPKRRKSVTGEIVLITGAGHGI GRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNRE DIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAH FWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKT LTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMH GILTEQKMIFIPSSIAFLTTLERILPERFLAVLKQKI
    • 分子量31 kDa including tags
    • 氨基酸20 to 285
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab101826 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 95 % SDS-PAGE.
    ab101826 was purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • 17 beta HSD 11
    • 17 beta HSD XI
    • 17 BETA HSD11
    • 17 BETA HSDXI
    • 17 beta hydroxysteroid dehydrogenase 11
    • 17 beta hydroxysteroid dehydrogenase type XI
    • 17 beta hydroxysteroid dehydrogenase XI
    • 17-beta-HSD 11
    • 17-beta-HSD XI
    • 17-beta-hydroxysteroid dehydrogenase 11
    • 17-beta-hydroxysteroid dehydrogenase XI
    • 17betaHSD11
    • 17betaHSDXI
    • 17bHSD11
    • CTCL associated antigen HD CL 03
    • CTCL tumor antigen HD CL 03
    • CTCL-associated antigen HD-CL-03
    • Cutaneous T cell lymphoma associated antigen HD CL 03
    • Cutaneous T-cell lymphoma-associated antigen HD-CL-03
    • Dehydrogenase/reductase SDR family member 8
    • DHB11_HUMAN
    • DHRS8
    • Estradiol 17 beta dehydrogenase 11
    • Estradiol 17-beta-dehydrogenase 11
    • Hsd17b11
    • Hydroxysteroid (17 beta) dehydrogenase 11
    • PAN1B
    • Retinal short chain dehydrogenase/reductase 2
    • Retinal short-chain dehydrogenase/reductase 2
    • RETSDR2
    • SDR16C2
    • SDR2
    • Short chain dehydrogenase/reductase family 16C member 2
    • T cell lymphoma associated antigen HD CL 03
    see all
  • 功能Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
  • 组织特异性Present at high level in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig cells, and granulosa cells of the dominant follicle and corpus luteum. In lung, it is detected in the ciliated epithelium and in acini of adult trachea, in bronchioles, but not in alveoli. In the eye, it is detected in the nonpigmented epithelium of the ciliary body and, at lower level, in the inner nuclear layer of the retina (at protein level). Widely expressed. Highly expressed in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart.
  • 序列相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant Human Hsd17b11 protein 图像

  • 15% SDS-PAGE analysis of 3µg ab101826

Recombinant Human Hsd17b11 protein (ab101826)参考文献

ab101826 has not yet been referenced specifically in any publications.

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