重组人HOXD10蛋白(ab152459)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQT CGLLPSLAKREVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPT CSFTTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVENPEVPVPG YFRLSQTYATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQMEKK MNEPVSGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSSPEVQEKESKEE IKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEIS KSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
    • 分子量
      65 kDa including tags
    • 氨基酸
      1 to 340

技术指标

Our Abpromise guarantee covers the use of ab152459 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • AI385591
    • AI874987
    • Homeo box 4D
    • Homeo box D10
    • Homeobox D10
    • Homeobox protein Hox-4D
    • Homeobox protein Hox-4E
    • Homeobox protein Hox-D10
    • Hox 4.4
    • Hox 4.5
    • Hox 4D
    • Hox 4E
    • Hox 5.3
    • HOX4D
    • HOX4E
    • HOXD10
    • HXD10
    • HXD10_HUMAN
    • OTTMUSP00000017845
    • RP23-313J15.9
    see all
  • 功能
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 组织特异性
    Strongly expressed in the adult male and female urogenital tracts.
  • 疾病相关
    Defects in HOXD10 are a cause of congenital vertical talus (CVT) [MIM:192950]; also known as rocker-bottom foot deformity or congenital convex pes valgus. CVT is a dislocation of the talonavicular joint, with rigid dorsal dislocation of the navicular over the neck of the talus. This condition is usually associated with multiple other congenital deformities and only rarely is an isolated deformity.
  • 序列相似性
    Belongs to the Abd-B homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 发展阶段
    Expressed in the developing limb buds.
  • 细胞定位
    Nucleus.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152459 stained with Coomassie Blue.

文献

ab152459 has not yet been referenced specifically in any publications.

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