Recombinant人hnRNP F protein (ab114680)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MMLGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTRE GRQSGEAFVELGSEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHS GPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGK ITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLK FMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYSTGYGGYEEYSGLS DGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKA TENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA NMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGC YGAGYSGQNSMGGYD
    • 分子量
      72 kDa including tags
    • 氨基酸
      1 to 415

技术指标

Our Abpromise guarantee covers the use of ab114680 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Heterogeneous nuclear ribonucleoprotein F
    • hnRNP F
    • HnRNP F protein
    • Hnrnpf
    • HNRPF
    • HNRPF_HUMAN
    • mcs94 1
    • MGC110997
    • N-terminally processed
    • Nucleolin like protein
    • Nucleolin like protein mcs94 1
    • Nucleolin-like protein mcs94-1
    • OK/SW-cl.23
    • OTTHUMP00000019482
    • OTTHUMP00000043413
    • OTTHUMP00000043414
    • Ribonucleoprotein F
    see all
  • 功能
    Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
  • 组织特异性
    Expressed ubiquitously.
  • 序列相似性
    Contains 3 RRM (RNA recognition motif) domains.
  • 结构域
    The N-terminal RRM domains are responsible for recognizing the G-tract of BCL-X RNA.
  • 翻译后修饰
    Phosphorylated upon DNA damage, probably by ATM or ATR.
    Sumoylated.
  • 细胞定位
    Nucleus > nucleoplasm.
  • Information by UniProt

图片

  • ab114680 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

文献

ab114680 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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