Recombinant人hnRNP A1 protein (ab123212)

概述

  • 产品名称Recombinant人hnRNP A1 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP09651-2
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MGSMSKSESP KEPEQLRKLF IGGLSFETTD ESLRSHFEQW GTLTDCVVMR DPNTKRSRGF GFVTYATVEE VDAAMNARPH KVDGRVVEPK RAVSREDSQR PGAHLTVKKI FVGGIKEDTE EHHLRDYFEQ YGKIEVIEIM TDRGSGKKRG FAFVTFDDHD SVDKIVIQKY HTVNGHNCEV RKALSKQEMA SASSSQRGRS GSGNFGGGRG GGFGGNDNFG RGGNFSGRGG FGGSRGGGGY GGSGDGYNGF GNDGSNFGGG GSYNDFGNYN NQSSNFGPMK GGNFGGRSSG PYGGGGQYFA KPRNQGGYGG SSSSSSYGSG RRF
    • 分子量37 kDa including tags
    • 氨基酸1 to 320
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab123212 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 85 % SDS-PAGE.
    ab123212 was purified using conventional chromatography and is > 85% pure by SDS - PAGE.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride

常规信息

  • 别名
    • HNRNPA 1
    • Helix destabilizing protein
    • Helix-destabilizing protein
    • Heterogeneous nuclear ribonucleoprotein A1
    • Heterogeneous nuclear ribonucleoprotein A1B protein
    • Heterogeneous nuclear ribonucleoprotein B2 protein
    • Heterogeneous nuclear ribonucleoprotein core protein A1
    • hnRNP A1
    • hnRNP core protein A1
    • HNRNPA1
    • HNRPA1
    • MGC102835
    • Nuclear ribonucleoprotein particle A1 protein
    • ROA1_HUMAN
    • Single strand DNA binding protein UP1
    • Single strand RNA binding protein
    • Single-strand RNA-binding protein
    see all
  • 功能Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.
  • 序列相似性Contains 2 RRM (RNA recognition motif) domains.
  • 翻译后修饰Arg-194, Arg-206 and Arg-225 are dimethylated, probably to asymmetric dimethylarginine.
    Sumoylated.
  • 细胞定位Nucleus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles continuously between the nucleus and the cytoplasm along with mRNA. Component of ribonucleosomes. In the course of viral infection, colocalizes with HCV NS5B at speckles in the cytoplasm in a HCV-replication dependent manner.
  • Information by UniProt

Recombinant Human hnRNP A1 protein 图像

  • 15% SDS-PAGE analysis of ab123212 (3 µg)

Recombinant Human hnRNP A1 protein (ab123212)参考文献

ab123212 has not yet been referenced specifically in any publications.

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Regrettably, the biological activity of this product has not yet been tested. Although it is scheduled to be tested eventually, we can’t give you a specific date on when we will have the results.
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