Guanine nucleotide binding protein (G protein) q polypeptide
Guanine nucleotide binding protein alpha q
Guanine nucleotide binding protein G(q) subunit alpha
Heterotrimeric guanine nucleotide-binding protein alpha q subunit
Histamine receptor H2
相关性Histamine H2 Receptor belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation.
Guanine nucleotide-binding proteins (G proteins) are a family of heterotrimeric proteins that couple cell surface, G protein-coupled receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit.
Gq alpha is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.