Recombinant人HIF1AN protein (ab86916)

概述

  • 产品名称Recombinant人HIF1AN protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MAATAAEAVA SGSGEPREEA GALGPAWDES QLRSYSFPTR PIPRLSQSDP RAEELIENEE PVVLTDTNLV YPALKWDLEY LQENIGNGDF SVYSASTHKF LYYDEKKMAN FQNFKPRSNR EEMKFHEFVE KLQDIQQRGG EERLYLQQTL NDTVGRKIVM DFLGFNWNWI NKQQGKRGWG QLTSNLLLIG MEGNVTPAHY DEQQNFFAQI KGYKRCILFP PDQFECLYPY PVHHPCDRQS QVDFDNPDYE RFPNFQNVVG YETVVGPGDV LYIPMYWWHH IESLLNGGIT ITVNFWYKGA PTPKRIEYPL KAHQKVAIMR NIEKMLGEAL GNPQEVGPLL NTMIKGRYN

技术指标

Our Abpromise guarantee covers the use of ab86916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab86916 was purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • DKFZp762F1811
    • Factor inhibiting HIF-1
    • Factor inhibiting HIF1
    • FIH 1
    • FIH-1
    • FIH1
    • FLJ20615
    • FLJ22027
    • HIF1AN
    • HIF1N_HUMAN
    • Hypoxia inducible factor 1 alpha inhibitor
    • Hypoxia inducible factor 1 alpha subunit inhibitor
    • Hypoxia inducible factor asparagine hydroxylase
    • Hypoxia-inducible factor 1-alpha inhibitor
    • Hypoxia-inducible factor asparagine hydroxylase
    • Peptide aspartate beta dioxygenase
    see all
  • 功能Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.
  • 序列相似性Contains 1 JmjC domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human HIF1AN protein 图像

  • 15% SDS-PAGE analysis of 3µg ab86916

Recombinant Human HIF1AN protein (ab86916)参考文献

ab86916 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"