Recombinant人HePTP / PTPN7 protein (ab61136)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human

技术指标

Our Abpromise guarantee covers the use of ab61136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Functional Studies

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 30% Glycerol, 50mM Sodium chloride, 20mM MOPS, 0.25mM DTT, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • BPTP 4
    • BPTP4
    • Dual specificity phosphatase 1
    • Hematopoietic protein tyrosine phosphatase
    • Hematopoietic protein-tyrosine phosphatase
    • HEPTP
    • LC PTP
    • LCPTP
    • LPTP
    • Protein tyrosine phoshatase non receptor type stress induced
    • Protein tyrosine phoshatase nonreceptor type stress induced
    • Protein tyrosine phosphatase LC PTP
    • Protein tyrosine phosphatase non receptor type 7
    • Protein-tyrosine phosphatase LC-PTP
    • PTN7_HUMAN
    • PTPN 7
    • Ptpn7
    • PTPNI
    • Tyrosine protein phosphatase non receptor type 7
    • Tyrosine-protein phosphatase non-receptor type 7
    see all
  • 功能
    Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
  • 组织特异性
    Expressed exclusively in thymus and spleen.
  • 序列相似性
    Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • 翻译后修饰
    Phosphorylated on serine residues in resting T-cells. Phosphorylation increases upon exposure to stimuli that increase intracellular cAMP levels. Phosphorylation leads to dissociation of bound MAP kinases.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

图片

  • Sample Kinase Activity Plot.
  • ab61136 on SDS-PAGE, MW ~67 kDa.

文献

ab61136 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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