Recombinant人HePTP / PTPN7 protein (ab124560)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHH SSGLVPRGSH MGSHMVQAHG GRSRAQPLTL SLGAAMTQPP PEKTPAKKHV RLQERRGSNV ALMLDVRSLG AVEPICSVNT PREVTLHFLR TAGHPLTRWA LQRQPPSPKQ LEEEFLKIPS NFVSPEDLDI PGHASKDRYK TILPNPQSRV CLGRAQSQED GDYINANYIR GYDGKEKVYI ATQGPMPNTV SDFWEMVWQE EVSLIVMLTQ LREGKEKCVH YWPTEEETYG PFQIRIQDMK ECPEYTVRQL TIQYQEERRS VKHILFSAWP DHQTPESAGP LLRLVAEVEE SPETAAHPGP IVVHCSAGIG RTGCFIATRI GCQQLKARGE VDILGIVCQL RLDRGGMIQT AEQYQFLHHT LALYAGQLPE EPSP
    • 分子量
      43 kDa including tags
    • 氨基酸
      1 to 360
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab124560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    Purified by using conventional chromatography.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

常规信息

  • 别名
    • BPTP 4
    • BPTP4
    • Dual specificity phosphatase 1
    • Hematopoietic protein tyrosine phosphatase
    • Hematopoietic protein-tyrosine phosphatase
    • HEPTP
    • LC PTP
    • LCPTP
    • LPTP
    • Protein tyrosine phoshatase non receptor type stress induced
    • Protein tyrosine phoshatase nonreceptor type stress induced
    • Protein tyrosine phosphatase LC PTP
    • Protein tyrosine phosphatase non receptor type 7
    • Protein-tyrosine phosphatase LC-PTP
    • PTN7_HUMAN
    • PTPN 7
    • Ptpn7
    • PTPNI
    • Tyrosine protein phosphatase non receptor type 7
    • Tyrosine-protein phosphatase non-receptor type 7
    see all
  • 功能
    Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
  • 组织特异性
    Expressed exclusively in thymus and spleen.
  • 序列相似性
    Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • 翻译后修饰
    Phosphorylated on serine residues in resting T-cells. Phosphorylation increases upon exposure to stimuli that increase intracellular cAMP levels. Phosphorylation leads to dissociation of bound MAP kinases.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

图片

  • 15% SDS-PAGE (3 µg loaded)

文献

ab124560 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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