Recombinant人HePTP / PTPN7 protein (ab124560)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ5SXQ0
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MGSHMVQAHG GRSRAQPLTL SLGAAMTQPP PEKTPAKKHV RLQERRGSNV ALMLDVRSLG AVEPICSVNT PREVTLHFLR TAGHPLTRWA LQRQPPSPKQ LEEEFLKIPS NFVSPEDLDI PGHASKDRYK TILPNPQSRV CLGRAQSQED GDYINANYIR GYDGKEKVYI ATQGPMPNTV SDFWEMVWQE EVSLIVMLTQ LREGKEKCVH YWPTEEETYG PFQIRIQDMK ECPEYTVRQL TIQYQEERRS VKHILFSAWP DHQTPESAGP LLRLVAEVEE SPETAAHPGP IVVHCSAGIG RTGCFIATRI GCQQLKARGE VDILGIVCQL RLDRGGMIQT AEQYQFLHHT LALYAGQLPE EPSP
    • 分子量43 kDa including tags
    • 氨基酸1 to 360
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab124560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    Purified by using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

常规信息

  • 别名
    • BPTP 4
    • BPTP4
    • Dual specificity phosphatase 1
    • Hematopoietic protein tyrosine phosphatase
    • Hematopoietic protein-tyrosine phosphatase
    • HEPTP
    • LC PTP
    • LCPTP
    • LPTP
    • Protein tyrosine phoshatase non receptor type stress induced
    • Protein tyrosine phoshatase nonreceptor type stress induced
    • Protein tyrosine phosphatase LC PTP
    • Protein tyrosine phosphatase non receptor type 7
    • Protein-tyrosine phosphatase LC-PTP
    • PTN7_HUMAN
    • PTPN 7
    • Ptpn7
    • PTPNI
    • Tyrosine protein phosphatase non receptor type 7
    • Tyrosine-protein phosphatase non-receptor type 7
    see all
  • 功能Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
  • 组织特异性Expressed exclusively in thymus and spleen.
  • 序列相似性Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • 翻译后修饰Phosphorylated on serine residues in resting T-cells. Phosphorylation increases upon exposure to stimuli that increase intracellular cAMP levels. Phosphorylation leads to dissociation of bound MAP kinases.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human HePTP / PTPN7 protein 图像

  • 15% SDS-PAGE (3 µg loaded)

Recombinant Human HePTP / PTPN7 protein (ab124560)参考文献

ab124560 has not yet been referenced specifically in any publications.

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