功能Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
序列相似性Belongs to the heme oxygenase family. Contains 2 HRM (heme regulatory motif) repeats.
SDS-PAGE - Heme oxygenase 2 protein (Human) (ab93468)
15% SDS-PAGE analysis of ab93468 (3µg).
Recombinant Human Heme oxygenase 2 protein (ab93468)参考文献
This product has been referenced in:
Alba-Castellón L et al. Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis. Cancer Res76:6205-6217 (2016).
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