Recombinant人Hck protein (ab90195)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 氨基酸78 to 138

技术指标

Our Abpromise guarantee covers the use of ab90195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    Purified by affinity chromatography
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -20ºC. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • Bmk
    • Hck
    • Hck 1
    • HCK_HUMAN
    • Hemopoietic cell kinase
    • JTK9
    • p59-HCK/p60-HCK
    • p59Hck
    • p59HCK/p60HCK
    • p61Hck
    • Tyrosine protein kinase HCK
    • Tyrosine-protein kinase HCK
    see all
  • 功能May serve as part of a signaling pathway coupling the Fc receptor to the activation of the respiratory burst. May also contribute to neutrophil migration and may regulate the degranulation process of neutrophils.
  • 组织特异性Expressed predominantly in cells of the myeloid and B-lymphoid lineages.
  • 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • 结构域The SH3 domain mediates binding to HIV-1 Nef.
  • 细胞定位Membrane. Cytoplasm. At least half of this isoform is found in the cytoplasm, some of this fraction is myristoylated and Membrane. Membrane > caveola. 20% of this isoform is associated with caveolae, this association depends on palmitoylation of cyteine at position 3.
  • Information by UniProt

Recombinant Human Hck protein (ab90195)参考文献

ab90195 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab90195.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"