Recombinant人HABP2 protein (ab114685)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ14520
    • 种属Human
    • 序列GNKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVC RPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRG
    • 分子量37 kDa including tags
    • 氨基酸105 to 204

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技术指标

Our Abpromise guarantee covers the use of ab114685 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Factor seven activating protease
    • Factor seven-activating protease
    • Factor VII activating protein
    • Factor VII-activating protease
    • FSAP
    • HABP
    • HABP 2
    • Habp2
    • HABP2_HUMAN
    • Hepatocyte growth factor activator like protein
    • Hepatocyte growth factor activator-like protein
    • HGFAL
    • Hyaluronan binding protein 2
    • Hyaluronan-binding protein 2 27 kDa light chain alternate form
    • Hyaluronic acid binding protein 2
    • PHBP
    • Plasma hyaluronan binding protein
    • Plasma hyaluronan-binding protein
    see all
  • 功能Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII.
  • 组织特异性Ubiquitously expressed.
  • 序列相似性Belongs to the peptidase S1 family.
    Contains 3 EGF-like domains.
    Contains 1 kringle domain.
    Contains 1 peptidase S1 domain.
  • 翻译后修饰Proteolytic cleavage at Gly-23 or Met-27 can give rise to the 50 kDa heavy chain and cleavage at Arg-313 or Lys-319 can give rise to the 27 kDa light chain. The heavy chain can undergo further proteolytic cleavage at Lys-169 or Arg-170 to give rise to 2 inactive 26 kDa fragments and the light chain can undergo further proteolytic cleavage at Arg-480 to give rise to inactive 17 kDa and 8 kDa fragments.
  • 细胞定位Secreted. Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
  • Information by UniProt

Recombinant Human HABP2 protein 图像

  • ab114685 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Recombinant Human HABP2 protein (ab114685)参考文献

ab114685 has not yet been referenced specifically in any publications.

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