General transcription factor IIF, polypeptide 2, 30kDa
Transcription initiation factor IIF subunit beta
Transcription initiation factor RAP30
功能TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
序列相似性Belongs to the TFIIF beta subunit family.
翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.