Recombinant人GRIK1 protein (ab116734)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      VAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNK TNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMT DSNKDKSSNI
    • 分子量
      38 kDa including tags
    • 氨基酸
      331 to 440

技术指标

Our Abpromise guarantee covers the use of ab116734 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • EAA3
    • EEA3
    • Excitatory amino acid receptor 3
    • GLR5
    • GluR-5
    • GluR5
    • GluR6
    • GluR7
    • Glutamate receptor
    • Glutamate receptor 5
    • Glutamate receptor ionotropic kainate 1
    • GRIK1
    • GRIK1_HUMAN
    • Human glutamate receptor GLUR5
    • ionotropic kainate 1
    • OTTHUMP00000096569
    see all
  • 功能
    Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
  • 组织特异性
    Most abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus.
  • 序列相似性
    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK1 subfamily.
  • 细胞定位
    Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE of ab116734 stained with Coomassie Blue.

文献

ab116734 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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