Recombinant人Granzyme A protein (ab114751)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP12544
    • 种属Human
    • 序列PYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEP TKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGD D
    • 分子量37 kDa including tags
    • 氨基酸41 to 141

技术指标

Our Abpromise guarantee covers the use of ab114751 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • CTL tryptase
    • CTLA3
    • Cytolytic t cell and natural killer cell specific trypsin like serine protease
    • Cytotoxic T lymphocyte associated serine esterase 3
    • Cytotoxic T lymphocyte proteinase 1
    • Cytotoxic T-lymphocyte proteinase 1
    • Fragmentin 1
    • Fragmentin-1
    • GRAA_HUMAN
    • Granzyme 1 cytotoxic T lymphocyte associated serine esterase 3
    • Granzyme A
    • Granzyme A (Cytotoxic T lymphocyte associated serine esterase 3; Hanukah factor serine protease)
    • Granzyme A (granzyme 1, cytotoxic T lymphocyte associated serine esterase 3)
    • Granzyme A precursor
    • Granzyme-1
    • GZMA
    • H factor
    • Hanukah factor serine protease
    • Hanukkah factor
    • HF
    • HFSP
    • TSP1
    see all
  • 功能This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Involved in apoptosis.
  • 序列相似性Belongs to the peptidase S1 family. Granzyme subfamily.
    Contains 1 peptidase S1 domain.
  • 细胞定位Secreted. Cytoplasmic granule.
  • Information by UniProt

Recombinant Human Granzyme A protein 图像

  • 12.5% SDS-PAGE Stained with Coomassie Blue showing ab114751 at approximately 36.74kDa.

Recombinant Human Granzyme A protein (ab114751)参考文献

ab114751 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"