Recombinant人Grancalcin protein (ab103054)

概述

  • 产品名称
    Recombinant人Grancalcin protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMAYPGYGGGFGNFSIQVPGMQMGQPVPETG PAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLTQS GINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMT VDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA CCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI
    • 分子量
      26 kDa including tags
    • 氨基酸
      1 to 217
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab103054 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 95 % SDS-PAGE.
    ab103054 was purified using conventional chromatography.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • GCA
    • GCL
  • 相关性
    Grancalcin is a calcium binding protein abundant in neutrophils and macrophages. It belongs to the penta EF hand subfamily of proteins which includes sorcin, calpain, and ALG2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule membrane fusion and degranulation.
  • 细胞定位
    50% cytoplasmic, the remainder being attached to the membranes and granules.

图片

  • 15% SDS-PAGE analysis of 3µg ab103054.

文献

ab103054 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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