Recombinant人Glycerol kinase protein (ab114846)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      AASKKAVLGPLVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQEFPREG WVEQDPKEILHSVYECIEKTCEKLGQLNIDISNIKAIGVSNQR
    • 分子量
      36 kDa including tags
    • 氨基酸
      2 to 94

技术指标

Our Abpromise guarantee covers the use of ab114846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • ATP glycerol 3 phosphotransferase
    • ATP:glycerol 3 phosphotransferase
    • ATP:glycerol 3-phosphotransferase
    • D930012N15Rik
    • GK
    • GK1
    • GKD
    • GLPK_HUMAN
    • Glycerokinase
    • Glycerol kinase
    • OTTHUMP00000023108
    • OTTHUMP00000023109
    • OTTHUMP00000215321
    see all
  • 功能
    Key enzyme in the regulation of glycerol uptake and metabolism.
  • 组织特异性
    Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.
  • 通路
    Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
  • 疾病相关
    Defects in GK are the cause of GK deficiency (GKD) [MIM:307030]. This disease can be either symptomatic with episodic metabolic and CNS decompensation or asymptomatic with hyperglycerolemia and hyperglyceroluria only.
  • 序列相似性
    Belongs to the FGGY kinase family.
  • 细胞定位
    Mitochondrion outer membrane. Cytoplasm. In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.
  • Information by UniProt

图片

  • ab114846 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

文献

ab114846 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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