Recombinant人glucose-6-phosphatase, catalytic subunit protein (ab114563)

概述

  • 产品名称Recombinant人glucose-6-phosphatase, catalytic subunit protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP35575
    • 种属Human
    • 序列MEEGMNVLHDFGIQSTHYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIW FHLQEAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSVP LIKQFPVTCETGPGSPSGHAMGTAGVYYVMVTSTLSIFQGKIKPTYRFRC LNVILWLGFWAVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVAETFSHIHS IYNASLKKYFLITFFLFSFAIGFYLLLKGLGVDLLWTLEKAQRWCEQPEW VHIDTTPFASLLKNLGTLFGLGLALNSSMYRESCKGKLSKWLPFRLSSIV ASLVLLHVFDSLKPPSQVELVFYVLSFCKSAVVPLASVSVIPYCLAQVLG QPHKKSL
    • 分子量65 kDa including tags
    • 氨基酸1 to 357

技术指标

Our Abpromise guarantee covers the use of ab114563 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • AW107337
    • G-6-Pase
    • G6Pase
    • G6Pase-alpha
    • g6pc
    • G6PC_HUMAN
    • G6PT
    • Glucose-6-phosphatase
    • Glucose-6-phosphatase alpha
    • GSD1
    • GSD1a
    • MGC163350
    • MGC93613
    • RP23-281C18.19
    see all
  • 功能Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.
  • 通路Carbohydrate biosynthesis; gluconeogenesis.
  • 疾病相关Defects in G6PC are the cause of glycogen storage disease type 1A (GSD1A) [MIM:232200]. A metabolic disorder characterized by impairment of terminal steps of glycogenolysis and gluconeogenesis. Patients manifest a wide range of clinical symptoms and biochemical abnormalities, including hypoglycemia, severe hepatomegaly due to excessive accumulation of glycogen, kidney enlargement, growth retardation, lactic acidemia, hyperlipidemia, and hyperuricemia.
  • 序列相似性Belongs to the glucose-6-phosphatase family.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt

Recombinant Human glucose-6-phosphatase, catalytic subunit protein 图像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

Recombinant Human glucose-6-phosphatase, catalytic subunit protein (ab114563)参考文献

ab114563 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114563.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"