Recombinant人GH2 protein (ab68364)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab68364 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性ab68364 is devoid of lactogenic (prolactin receptor mediated) activity characteristic to pituitary GHs.
  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab68364 is purified by proprietary chromatographic techniques.
  • 形式Lyophilised
  • 补充说明Upon reconstitution and filter sterilization ab68364 can be stored at 4°C for up to 4 weeks. For long term storage and more diluted solutions it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 0.0045mM Sodium bicarbonate, pH 11

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶It is recommended to reconstitute the lyophilized Placental Growth Hormone in 0.4% NaHCO3 or water adjusted to pH 11, not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

常规信息

  • 别名
    • GH 2
    • GH V
    • GH2
    • GHL
    • GHV
    • Growth hormone 2
    • Growth hormone variant
    • hGH V
    • hGHV
    • Placenta specific growth hormone
    • Placental specific growth hormone
    see all
  • 相关性Growth hormone 2 (GH2) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. The major role of GH2 in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
  • 细胞定位Secreted

Recombinant human GH2 protein (ab68364)参考文献

ab68364 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"