概述

  • 产品名称
    重组人GDF6蛋白
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 序列
      TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR

技术指标

Our Abpromise guarantee covers the use of ab50230 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    Functional Studies

    SDS-PAGE

  • 内毒素水平
    < 0.100 Eu/µg
  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).

  • 复溶
    Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

常规信息

  • 别名
    • bmp 13
    • bmp13
    • Cartilage Derived Morphogenetic Protein 2
    • cdmp 2
    • CDMP2
    • gdf 6
    • GDF16
    • Growth differentiation factor 6
    • Growth/differentiation factor 16
    • Growth/differentiation factor 6
    • KFM
    • KFS
    • KFS1
    • KFSL
    • Klip Feil malformation
    • Klippel Feil malformation
    • Klippel Feil syndrome
    • LCA17
    • MCOP4
    • MCOPCB6
    • SCDO4
    • SGM1
    see all
  • 相关性
    GDF6 (Growth/differentiation factor 6) is expressed in hypertrophic chondrocytes during embryonic development of long bones and is required for normal formation of bones and joints in the limbs, skull, and axial skeleton. It plays a key role in establishing boundaries between skeletal elements during development. The functional form of GDF6 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains obtained by proteolytic processing of a biologically inactive precursor protein.
  • 细胞定位
    Secreted

图片

  • All lanes : Anti-GDF6 antibody (ab73288) at 1 µg/ml

    Lane 1 : Recombinant Human GDF6 protein (ab50230) at 0.1 µg
    Lane 2 : Recombinant Human GDF6 protein (ab50230) at 0.01 µg

    Secondary
    All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Exposure time: 30 seconds


    ab50230 is a homodimer consisting of two 120aa monomers. The homodimer format is expected to run at 27kDa, so the observed band is thought to be the monomer form.

文献

ab50230 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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