Recombinant人GDF15 protein (ab50077)

概述

描述

  • 性质Recombinant
  • 来源Mammalian
  • 氨基酸序列
    • AccessionQ99988
    • 种属Human
    • 序列ARNGDHCPLGPGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPS QFRAANMHAQIKTSLHRLKPDTVPAPCCVPASYNPMVLIQKTDTGVSLQT YDDLLAKDCHCI
    • 氨基酸197 to 308
    • 额外的序列信息This product refers to the processed mature form of this protein from aa 195 to 308. Therefore it does not contain the signal peptide or propeptide.

技术指标

Our Abpromise guarantee covers the use of ab50077 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性

    Determined by its ability to inhibit alkaline phosphatase activity in differentiating MC3T3/E1 osetoblast cells. The expected ED50 for this effect is 1.0-3.0 μg/ml.

  • 应用

    Functional Studies

    SDS-PAGE

  • 内毒素水平< 1.000 Eu/µg
  • 纯度> 98 % SDS-PAGE.
    ab50077 purity was determined also by HPLC Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Reconstitute to 1mg/ml with distilled water.

常规信息

  • 别名
    • GDF 15
    • GDF-15
    • Gdf15
    • GDF15_HUMAN
    • Growth differentiation factor 15
    • Growth/differentiation factor 15
    • Macrophage inhibitory cytokine 1
    • MIC 1
    • Mic-1
    • MIC1
    • NAG 1
    • NAG-1
    • NAG1
    • NRG 1
    • NRG-1
    • NRG1
    • NSAID
    • NSAID (nonsteroidal anti inflammatory drug) activated protein 1
    • NSAID regulated protein 1
    • NSAID-activated gene 1 protein
    • NSAID-regulated gene 1 protein
    • PDF
    • PLAB
    • Placental bone morphogenetic protein
    • Placental bone morphogenic protein
    • Placental TGF beta
    • Placental TGF-beta
    • Prostate differentiation factor
    • PTGF beta
    • PTGFB
    see all
  • 组织特异性Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
  • 序列相似性Belongs to the TGF-beta family.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant human GDF15 protein (ab50077)参考文献

ab50077 has not yet been referenced specifically in any publications.

Product Wall

I have received from the lab further information about ab50077. This product was lyophilized from 10 mM Sodium Citrate, pH 3.0.

I can confirm that the GDF15 protein ab50077 is naturally secreted by a proprietary cell line and then purified. No recombinant techniques are involved in the production of this protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"