Recombinant人GALNT2 protein (ab114957)

概述

  • 产品名称Recombinant人GALNT2 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ10471
    • 种属Human
    • 序列CHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKW EQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLNLQQ
    • 分子量37 kDa including tags
    • 氨基酸473 to 571

技术指标

Our Abpromise guarantee covers the use of ab114957 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • GalNAc T2
    • GalNAc-T2
    • Galnt2
    • GALT2_HUMAN
    • GaNTase 2
    • Polypeptide GalNAc transferase 2
    • Polypeptide N acetylgalactosaminyltransferase 2
    • Polypeptide N acetylgalactosaminyltransferase 2 soluble form
    • Polypeptide N-acetylgalactosaminyltransferase 2 soluble form
    • pp GaNTase 2
    • pp-GaNTase 2
    • Protein UDP acetylgalactosaminyltransferase 2
    • Protein-UDP acetylgalactosaminyltransferase 2
    • UDP GalNAc transferase 2
    • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2
    • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2 (GalNAc T2)
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2
    see all
  • 功能Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region.
  • 组织特异性Widely expressed.
  • 通路Protein modification; protein glycosylation.
  • 序列相似性Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • 结构域There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • 细胞定位Golgi apparatus > Golgi stack membrane. Secreted. Resides preferentially in the trans and medial parts of the Golgi stack. A secreted form also exists.
  • Information by UniProt

Recombinant Human GALNT2 protein 图像

  • 12.5% SDS-PAGE showing ab114957 at approximately 36.52kDa.
    Stained with Coomassie Blue.

Recombinant Human GALNT2 protein (ab114957)参考文献

ab114957 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114957.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"