Recombinant人GALE protein (ab96767)

概述

  • 产品名称Recombinant人GALE protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ14376
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMAEKVLVTGGAGYIGSHTVLELLEAGYLPV VIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQRLFKKY SFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFS SSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDY DTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQM VQAMEKASGKKIPYKVVARREGDVAACYANPSLAQEELGWTAALGLDRMC EDLWRWQKQNPSGFGTQA
    • 分子量40 kDa including tags
    • 氨基酸1 to 348
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab96767 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab96767 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 5mM DTT, 20mM Tris HCl, 1mM EDTA, pH 8.0

常规信息

  • 别名
    • FLJ95174
    • FLJ97302
    • Galactose 4 epimerase UDP
    • Galactowaldenase
    • galE
    • GALE_HUMAN
    • OTTHUMP00000002991
    • OTTHUMP00000002994
    • OTTHUMP00000037931
    • OTTHUMP00000044857
    • SDR1E1
    • short chain dehydrogenase/reductase family 1E member 1
    • UDP galactose 4 epimerase
    • UDP galactose 4' epimerase
    • UDP glucose 4 epimerase
    • UDP-galactose 4-epimerase
    • UDP-glucose 4-epimerase
    see all
  • 功能Catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine.
  • 通路Carbohydrate metabolism; galactose metabolism.
  • 疾病相关Defects in GALE are the cause of epimerase-deficiency galactosemia (EDG) [MIM:230350]; also known as galactosemia type 3. Clinical features include early-onset cataracts, liver damage, deafness and mental retardation. There are two clinically distinct forms of EDG. (1) A benign, or 'peripheral' form with no detectable GALE activity in red blood cells and characterized by mild symptoms. Some patients may suffer no symptoms beyond raised levels of galactose-1-phosphate in the blood. (2) A much rarer 'generalized' form with undetectable levels of GALE activity in all tissues and resulting in severe features such as restricted growth and mental development.
  • 序列相似性Belongs to the sugar epimerase family.
  • Information by UniProt

Recombinant Human GALE protein 图像

  • 15% SDS-PAGE showing ab96767 at approximately 40.4kDa (3µg).

Recombinant Human GALE protein (ab96767)参考文献

ab96767 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab96767.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"