Recombinant人GAK protein (ab114800)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionO14976
    • 种属Human
    • 序列SAVAPTPATEGPLFSPGGQPAPCGSQASWTKSQNPDPFADLGDLSSGLQG SPAGFPPGGFIPKTATTPKGSSSWQTSRPPAQGASWPPQAKPPPKACTQP
    • 分子量37 kDa including tags
    • 氨基酸151 to 250

技术指标

Our Abpromise guarantee covers the use of ab114800 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Auxilin 2
    • Cyclin G associated kinase
    • Cyclin-G-associated kinase
    • DNAJ26
    • DNAJC26
    • EC 2.7.11.1
    • FLJ16629
    • FLJ40395
    • GAK
    • GAK protein
    • GAK_HUMAN
    • MGC99654
    see all
  • 功能Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
  • 组织特异性Ubiquitous. Highest in testis.
  • 序列相似性Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
    Contains 1 C2 tensin-type domain.
    Contains 1 J domain.
    Contains 1 phosphatase tensin-type domain.
    Contains 1 protein kinase domain.
  • 细胞定位Cytoplasm > perinuclear region. Golgi apparatus > trans-Golgi network. Cell junction > focal adhesion. Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focals adhesions.
  • Information by UniProt

Recombinant Human GAK protein 图像

  • ab114800 on 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human GAK protein (ab114800)参考文献

ab114800 has not yet been referenced specifically in any publications.

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