功能Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
组织特异性Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.
序列相似性Belongs to the MAP1 LC3 family.
翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.