Recombinant人GABA A Receptor beta 3 protein (ab114354)

概述

  • 产品名称
    Recombinant人GABA A Receptor beta 3 protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMV SEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLN DKKSFVHGVT
    • 分子量
      38 kDa including tags
    • 氨基酸
      26 to 135

技术指标

Our Abpromise guarantee covers the use of ab114354 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • ECA5
    • GABA alpha receptor beta-2 subunit
    • GABA(A) receptor subunit beta-3
    • GABAA receptor beta 3 subunit
    • GABAA receptor subunit beta 3
    • GABR B3
    • Gabrb3
    • Gamma aminobutyric acid (GABA) A receptor beta 3
    • Gamma aminobutyric acid receptor subunit beta 3
    • Gamma-aminobutyric acid receptor subunit beta-3
    • GBRB3_HUMAN
    • MGC9051
    see all
  • 功能
    Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
  • 疾病相关
    Epilepsy, childhood absence 5
  • 序列相似性
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB3 sub-subfamily.
  • 细胞定位
    Cell junction, synapse, postsynaptic cell membrane. Cell membrane.
  • Information by UniProt

图片

  • ab114354 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

文献

ab114354 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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