Recombinant人GAB1 protein (ab89815)

概述

描述

  • 性质
    Recombinant
  • 来源
    Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属
      Human

技术指标

Our Abpromise guarantee covers the use of ab89815 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: 150mM Imidazole
    Constituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 2mM DTT, 0.1mM PMSF, pH 7.0

常规信息

  • 别名
    • Gab 1
    • GAB1
    • GAB1_HUMAN
    • GRB 2 associated binder 1
    • GRB 2 associated binding protein 1
    • GRB2 associated binding protein 1 isoform a
    • GRB2 associated binding protein 1 isoform b
    • GRB2-associated binder 1
    • GRB2-associated-binding protein 1
    • Growth factor receptor bound protein 2-associated protein 1
    see all
  • 功能
    Probably involved in EGF and insulin receptor signaling.
  • 序列相似性
    Belongs to the GAB family.
    Contains 1 PH domain.
  • 翻译后修饰
    Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.
  • Information by UniProt

图片

  • SDS-PAGE showing ab89815 at approximately 108kDa.

文献

ab89815 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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